| Autor: | Ríos, Maritza, Villanueva, Carola, San Martín, Carolina, Ramírez, Eugenio |
| Revista: | Revista Médica De Chile |
| Año: | 2003 |
| Número: | 7 |
| Paginas: | 711-718 |
| Volumen: | 131 |
| Abstract: | BACKGROUND: Type I human immunodeficiency virus (HIV) is characterized by a great genetic variability. There are three groups of virus throughout the world: O, N and M. Group M is responsible for AIDS pandemic and is subdivided in 9 genetic subtypes. Most viral strains in South America are subtype B. AIM: To determine the frequency of HIV subtypes in Chilean patients. MATERIAL AND METHODS: Genetic analysis of C2-V3-C3 region of the gene env in HIV strains coming from 77 Chilean subjects infected by different means. DNA heteroduplex mobility assay was used to determine HIV subtypes. RESULTS: Sixty eight cases were infected with subtype B (88.3%) and nine cases were infected with subtype F (11.7%). CONCLUSIONS: Subtype B is the predominant HIV in Chile, but subtype F is also present. |
| Idioma: | Español |
| Base de Datos: | PubMed |
| Ver Más: | http://www.ncbi.nlm.nih.gov/pubmed/14513690 |