| Autor: | Ulloa, S., Bravo, C., Ramirez, E., Fasce, R., Fernandez, J. |
| Revista: | Journal of Virological Methods |
| Año: | 2021 |
| Número: | |
| Paginas: | 114216 |
| Volumen: | 295 |
| Abstract: | Currently, the rapid global spread of SARS-CoV-2 is related to G clade (including GH, GR, GRY and GV clades), which are associated with more than 98 % of sequenced viral isolates worldwide. The unprecedented velocity of spread of SARS-CoV-2 outbreak represents a critical need for prevention strategies. Vaccines are recently being available and antiviral drugs have shown limited efficacy in COVID-19 patients. Thus, it is needed to know how to reduce the infectivity of the virus by different physicochemical conditions in order to prevent exposure to contaminated material. This work describes heating and irradiating UV-C light procedures to reduce the infectivity of SARS-CoV-2 belonging to different three lineages. Results of physicochemical treatment showed no differences among viral lineages. Analytical conditions for efficient inactivation of SARS-CoV-2 were determined. |
| Idioma: | eng |
| Base de Datos: | PubMed |
| Ver Más: | https://doi.org/10.1016/j.jviromet.2021.114216 |