| Autor: | Tapia, Teresa, Olivares, María Fernanda, Stenos, John, Iglesias, Rodrigo, Díaz, Nora, Vergara, Natalia, Sotomayor, Viviana, Gallegos, Doris, Soares Magalhães, Ricardo J., Acevedo, Johanna, Araya, Pamela, Graves, Stephen R., Hormazabal, Juan Carlos |
| Revista: | Pathogens (Basel, Switzerland) |
| Año: | 2021 |
| Número: | 5 |
| Paginas: | 531 |
| Volumen: | 10 |
| Abstract: | Coxiella burnetii is an intracellular bacterium and the cause of the zoonotic infection, Q fever. National surveillance data on C. burnetii seroprevalence is currently not available for any South American country, making efforts of public health to implement strategies to mitigate infections in different at-risk groups within the population extremely challenging. In the current study, we used two commercial anti-C. burnetii immunoassays to screen sera collected from a sample of the Chilean population as part of a 2016-2017 national health survey (n = 5166), nationwide and age-standardized. The seroprevalence for C. burnetii for persons ? 15 years was estimated to be 3.0% (95% CI 2.2-4.0), a level similar to national surveys from The Netherlands (2.4%) and USA (3.1%), but lower than Australia (5.6%). A linear increase of C. burnetii seropositivity was associated with an individual's age, with the peak seroprevalence 5.6% (95% CI 3.6-8.6) observed in the ?65 years' group. C. burnetii seropositivity was significantly higher in the southern macro-zone 6.0% (95% CI 3.3-10.6) compared to metropolitan region 1.8% (95% CI 0.9-3.3), the former region being home to significant livestock industries, particularly dairy farming. These data will be useful to inform targeted strategies for the prevention of Q fever in at-risk populations in Chile. |
| Idioma: | eng |
| Base de Datos: | PubMed |
| Ver Más: | https://doi.org/10.3390/pathogens10050531 |