Autor: Cáceres, C.; Yung, V.; Araya, P.; Tognarelli, J.; Villagra, E.; Vera, L.; Fernández, J.
Revista: Archives of Virology
Año: 2008
Número: 10
Paginas: 1967-1970
Volumen: 153
Abstract: DInglesue-1 viruses responsible for the dInglesue fever outbreak in Easter Island in 2002 were isolated from acute-phase sera of dInglesue fever patients. In order to analyze the complete genome sequence, we designed primers to amplify contiguous segments across the entire sequence of the viral genome. RT-PCR products obtained were cloned, and complete nucleotide and deduced amino acid sequences were determined. This report constitutes the first complete genetic characterization of a DENV-1 isolate from Chile. Phylogenetic analysis shows that an Easter Island isolate is most closely related to Pacific DENV-1 genotype IV viruses.
Idioma: Ingles
Base de Datos: PubMed
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