| Escobar, Daniel F.; Diaz-Dinamarca, Diego A.; Hernández, Carlos F.; Soto, Daniel A.; Manzo, Ricardo A.; Alarcón, Pedro I.; Pinto, Camila H.; Bastias, Diego N.; Oberg-Bravo, Carolayn N.; Rojas, Robert; Illanes, Sebastián E.; Kalergis, Alexis M.; Vasquez, Abel E. |
Development and analytical validation of real-time PCR for the detection of Streptococcus agalactiae in pregnant women |
BACKGROUND: Group B Streptococcus (GBS) is the leading cause of invasive neonatal infection. In this study, we aimed to evaluate the analytical validation of qualitative real-time polymerase chain rea... |
2020 |
20 |
Ver Más |
| Cisterna, Bruno A.; Vargas, Aníbal A.; Puebla, Carlos; Fernández, Paola; Escamilla, Rosalba; Lagos, Carlos F.; Matus, María F.; Vilos, Cristian; Cea, Luis A.; Barnafi, Esteban; Gaete, Hugo; Escobar, Daniel F.; Cardozo, Christopher P.; Sáez, Juan C. |
Active acetylcholine receptors prevent the atrophy of skeletal muscles and favor reinnervation |
Denervation of skeletal muscles induces severe muscle atrophy, which is preceded by cellular alterations such as increased plasma membrane permeability, reduced resting membrane potential and accelera... |
2020 |
11 |
Ver Más |
| Chadha, Mandeep; Hirve, Siddhivinayak; Bancej, Christina; Barr, Ian; Baumeister, Elsa; Caetano, Braulia; Chittaganpitch, Malinee; Darmaa, Badarch; Ellis, Joanna; Fasce, Rodrigo; Kadjo, Herve; Jackson, Sandra; Leung, Vivian; Pisareva, Maria; Moyes, Jocelyn; Naguib, Amel; Tivane, Almiro; Zhang, Wenqing; WHO RSV Surveillance Group |
Human respiratory syncytial virus and influenza seasonality patterns-Early findings from the WHO global respiratory syncytial virus surveillance |
BACKGROUND: Human respiratory syncytial virus (RSV) causes illnesses among all age groups and presents a burden to healthcare services. To better understand the epidemiology and seasonality of RSV in ... |
2020 |
14 |
Ver Más |
| Tapia, Teresa; Stenos, John; Flores, Roberto; Duery, Oscar; Iglesias, Rodrigo; Olivares, Maria Fernanda; Gallegos, Doris; Rosas, Cristian; Wood, Heidi; Acevedo, Johanna; Araya, Pamela; Graves, Stephen R.; Hormazabal, Juan Carlos |
Evidence of Q Fever and Rickettsial Disease in Chile |
Q fever and rickettsial diseases occur throughout the world and appear to be emergent zoonoses in Chile. The diagnosis of these diseases is currently uncommon in Chile, as their clinical presentations... |
2020 |
5 |
Ver Más |
| Moreno, Jaime; Duarte, Carolina; Cassiolato, Ana Paula; Chacón, Grettel Chanto; Alarcon, Pedro; Sánchez, Jacqueline; Martín, Yolanda Narváez San; Valenzuela, Claudia; Castillo, Wendy; Gabarrot, Gabriela García; SIREVA II Group |
Molecular characterization of Latin American invasive Streptococcus pneumoniae serotype 19A isolates |
Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide, especially among children and the elderly. S. pneumoniae serotype 19A has emerged as a major cause of invasive disease i... |
2020 |
38 |
Ver Más |
| Diaz-Dinamarca, Diego A.; Hernandez, Carlos; Escobar, Daniel F.; Soto, Daniel A.; Muñoz, Guillermo A.; Badilla, Jesús F.; Manzo, Ricardo A.; Carrión, Flavio; Kalergis, Alexis M.; Vasquez, Abel E. |
Mucosal Vaccination with Lactococcus lactis-Secreting Surface Immunological Protein Induces Humoral and Cellular Immune Protection against Group B Streptococcus in a Murine Model |
Group B Streptococcus (GBS) is the primary etiological agent of sepsis and meningitis in newborns and is associated with premature birth and stillbirth. The development of a licensed vaccine is one of... |
2020 |
8 |
Ver Más |
| Barría, Carla; Singer, Randall S.; Bueno, Irene; Estrada, Erika; Rivera, Dácil; Ulloa, Soledad; Fernández, Jorge; Mardones, Fernando O.; Moreno-Switt, Andrea I. |
Tracing Listeria monocytogenes contamination in artisanal cheese to the processing environments in cheese producers in southern Chile |
Artisanal cheese from southern Chile is made primarily by rural families who raise dairy cows and produce cheese as a way to add value to their milk. The most common cheese produced is chanco, a semi-... |
2020 |
90 |
Ver Más |
| Vicencio, Emiliano; Cordero, Esteban M.; Cortés, Bastián I.; Palominos, Sebastián; Parra, Pedro; Mella, Tania; Henrríquez, Constanza; Salazar, Nelda; Monasterio, Gustavo; Cafferata, Emilio A.; Murgas, Paola; Vernal, Rolando; Cortez, Cristian |
Aggregatibacter Actinomycetemcomitans Induces Autophagy in Human Junctional Epithelium Keratinocytes |
The adverse environmental conditions found in the periodontium during periodontitis pathogenesis stimulate local autophagy responses, mainly due to a continuous inflammatory response against the dysbi... |
2020 |
9 |
Ver Más |
| Mungwira, Randy G.; Guillard, Christine; Saldaña, Adiela; Okabe, Nobuhiko; Petousis-Harris, Helen; Agbenu, Edinam; Rodewald, Lance; Zuber, Patrick L. F. |
Global landscape analysis of no-fault compensation programmes for vaccine injuries: A review and survey of implementing countries |
To update the landscape analysis of vaccine injuries no-fault compensation programmes, we conducted a scoping review and a survey of World Health Organization Member States. We describe the characteri... |
2020 |
15 |
Ver Más |
| Gregório, Maria João; Rodrigues, Ana M.; Salvador, Clara; Dias, Sara S.; de Sousa, Rute D.; Mendes, Jorge M.; Coelho, Pedro S.; Branco, Jaime C.; Lopes, Carla; Martínez-González, Miguel A.; Graça, Pedro; Canhão, Helena |
Validation of the Telephone-Administered Version of the Mediterranean Diet Adherence Screener (MEDAS) Questionnaire |
A 14-Item Mediterranean Diet Adherence Screener (MEDAS) questionnaire was developed and validated in face-to-face interviews, but not via telephone. The aims of this study were to evaluate the validit... |
2020 |
12 |
Ver Más |
| Bustos, Patricia; Tambley, Carolina; Acevedo, Alejandra; Andrade, Winston; Leal, Gabriel; Vidal, Deyanira; Roldán, Francisco; Fasce, Rodrigo; Ramírez, Eugenio
|
Quantitative detection of SARS-CoV-2 RNA in nasopharyngeal samples from infected patients with mild disease
|
Diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) cases is based on the count of real-time reverse transcription-plymerase chain reaction (RT-PCR) positive people. Viral load b... |
2020
|
|
Ver Más |
| Hens, Bart; Corsetti, Maura; Bermejo, Marival; Löbenberg, Raimar; González, Pablo M.; Mitra, Amitava; Desai, Divyakant; Chilukuri, Dakshina Murthy; Aceituno, Alexis |
"Development of Fixed Dose Combination Products" Workshop Report: Considerations of Gastrointestinal Physiology and Overall Development Strategy |
The gastrointestinal (GI) tract is one of the most popular and used routes of drug product administration due to the convenience for better patient compliance and reduced costs to the patient compared... |
2019 |
21 |
Ver Más |
| Balanda, Monserrat; Fernández, Jorge; Vergara, Nicolás; Campano, Constanza; Arata, Loredana; Martín, Héctor San; Ramírez, Eugenio |
Genetic variability of human papillomavirus type 66 L1 gene among women presenting for cervical cancer screening in Chile |
The high-risk human papillomaviruses (HR-HPVs) are involved in the development of cervical cancer. Nevertheless, there are differences in the oncogenic potential among them. HPV-16 and HPV-18 are asso... |
2019 |
208 |
Ver Más |
| Altamirano-Lagos, María José; Díaz, Fabián E.; Mansilla, Miguel Andrés; Rivera-Pérez, Daniela; Soto, Daniel; McGill, Jodi L.; Vasquez, Abel E.; Kalergis, Alexis M. |
Current Animal Models for Understanding the Pathology Caused by the Respiratory Syncytial Virus |
The human respiratory syncytial virus (hRSV) is the main etiologic agent of severe lower respiratory tract infections that affect young children throughout the world, associated with significant morbi... |
2019 |
10 |
Ver Más |
| Fica, Alberto; Sotomayor, Viviana; Fasce, Rodrigo; Dabanch, Jeannette; Soto, Andrés; Charpentier, Paulo; Guerrero, Gonzalo; Olivares, Felipe; Triantafilo, Vjera; Omeiri, Nathalie El; Gaínza-Lein, Marina |
Severe acute respiratory infections (SARI) from influenza in adult patients in Chile: the experience of a sentinel hospital |
Objective: To 1) describe clinical characteristics of adult patients in Chile with severe acute respiratory infections (SARI) associated with influenza viruses, and 2) analyze virus subtypes identifie... |
2019 |
43 |
Ver Más |
| Soto, Jorge A.; Diaz-Dinamarca, Diego A.; Soto, Daniel A.; Barrientos, Magaly J.; Carrión, Flavio; Kalergis, Alexis M.; Vasquez, Abel E. |
Cellular immune response induced by surface immunogenic protein with AbISCO-100 adjuvant vaccination decreases group B Streptococcus vaginal colonization |
Group B Streptococcus (GBS) represents one of the most common causes of bacterial infection in neonates; it is also associated with premature childbirth and stillbirth. A vaccine against GBS is needed... |
2019 |
111 |
Ver Más |
| Sánchez-Nieto, B.; López-Pineda, E.; Ruiz-Trejo, C.; Muñoz, I. D.; Caprile, P.; Chorbadjian, G.; Brandan, M. E. |
Dedicated phantom and TLD-100 dosimetry for simultaneous determination of mean glandular dose and beam quality: Proposal for a compact mammography quality control procedure |
... |
2019 |
60 |
Ver Más |
| Oyarte Galvez, Marcela; Cabiesses Valdés, Báltica; Pedrero Castillo, Victor |
[Poverty and Self-perceived health: Contrast between multidimensional poverty and income poverty] |
... |
2019 |
51 |
Ver Más |
| Aravena, Carmen; Valencia, Bárbara; Villegas, Andrea; Ortega, Mauricio; Fernández R, Alda; Araya R, Pamela; Saavedra, Aníbal; Del Campo, Rosa |
[Characterization of Salmonella Heidelberg strains isolated in Chile] |
BACKGROUND: Salmonella Heidelberg (S. Heidelberg) causes gastroenteritis and sometimes bacteremia and endocarditis. In other countries, this serovar has multidrug resistance including extended-spectru... |
2019 |
147 |
Ver Más |
| Jercic, María Isabel; Aguayo, Carolina; Saldarriaga-Córdoba, Mónica; Muiño, Laura; Chenet, Stella Maris; Lagos, Jaime; Osuna, Antonio; Fernández, Jorge |
Genotypic diversity of Acanthamoeba strains isolated from Chilean patients with Acanthamoeba keratitis |
BACKGROUND: Acanthamoeba spp. are the causative agents of a severe keratitis occurring mainly in contact lens wearers. The genus comprises more than 24 species that are currently divided into 20 diffe... |
2019 |
12 |
Ver Más |
